Description

(3S,4R)-4-Benzyl-3-(3-Methylpentanoyl)-Oxazolidin-2-One is a high-purity chiral auxiliary and synthetic intermediate of significant importance in asymmetric organic synthesis. Its well-defined stereochemistry provides a powerful tool for controlling the stereoselectivity of critical bond-forming reactions, enabling the production of enantiomerically pure compounds. This product is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries, particularly for the synthesis of complex, biologically active molecules.

Application

• As a chiral auxiliary in asymmetric aldol, alkylation, and Diels-Alder reactions.
• Key intermediate in the synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Building block for the development of novel catalysts and ligands used in stereoselective catalysis.
• Research and development of new synthetic methodologies in academic and industrial laboratories.
• Production of specialty fine chemicals and advanced materials where stereochemical control is paramount.
• Process development and scale-up for the manufacture of chiral drugs and agrochemicals.

Basic Information

Product Name	(3S,4R)-4-Benzyl-3-(3-Methylpentanoyl)-Oxazolidin-2-One
CAS No.	228267-64-9
Molecular Formula	C16H21NO3
Molecular Weight	275.34 g/mol
Synonyms	(3S,4R)-4-Benzyl-3-(3-methylpentanoyl)-2-oxazolidinone; (3S,4R)-4-Benzyl-3-(3-methyl-1-oxopentyl)-2-oxazolidinone; Evans Auxiliary Derivative; (3S,4R)-N-(3-Methylpentanoyl)-4-benzyl-2-oxazolidinone; (3S,4R)-4-Benzyl-3-(3-methylvaleryl)-2-oxazolidinone; (3S,4R)-3-(3-Methylpentanoyl)-4-benzyloxazolidin-2-one; Benzyl Oxazolidinone Chiral Auxiliary
EINECS	Contact for details

Quality Control

Our (3S,4R)-4-Benzyl-3-(3-Methylpentanoyl)-Oxazolidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.