Description

2,3,4-Trifluorophenylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through versatile cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is critically important for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise fluorination patterns to modulate the properties of their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated active pharmaceutical ingredients (APIs) and drug candidates, where fluorine atoms enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and pesticides, leveraging fluorine's ability to increase lipophilicity and environmental persistence.
• Material Science Research: Serves as a precursor for synthesizing fluorinated organic electronic materials, including OLEDs, liquid crystals, and polymers with tailored electronic properties.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to form biaryl and heterobiaryl structures, a cornerstone of modern C-C bond formation.
• Chemical Biology & Probe Development: Utilized in creating fluorinated molecular probes and tags for studying biological processes and diagnostics.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for bespoke synthesis projects requiring specific fluorinated aromatic motifs.

Basic Information

Product Name	2,3,4-Trifluorophenylboronic Acid
CAS No.	226396-32-3
Molecular Formula	C6H4BF3O2
Molecular Weight	175.90 g/mol
Synonyms	(2,3,4-Trifluorophenyl)boronic Acid; 2,3,4-Trifluorobenzeneboronic Acid; B-(2,3,4-Trifluorophenyl)boronic Acid; 2,3,4-Trifluorophenyl-Boronic Acid; Boronic acid, B-(2,3,4-trifluorophenyl)-; 226396-32-3; 2,3,4-Trifluorophenylboronic acid (contains varying amounts of Anhydride)
EINECS	Contact for details

Quality Control

Our 2,3,4-Trifluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	Conforms
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.