Description

2,4-Dibromo-3-(difluoromethoxy)benzoic acid is a high-purity, multi-functional aromatic building block of significant interest in advanced organic synthesis. Its unique halogenated and fluorinated structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a core building block for developing next-generation herbicides and fungicides, leveraging the difluoromethoxy group for enhanced bioactivity and metabolic stability.
• Material Science Research: Used in the development of specialty polymers and liquid crystal materials, where the bromine and fluorine substituents modify electronic and physical characteristics.
• Organic Light-Emitting Diodes (OLEDs): Acts as a starting material for synthesizing electron-transport or host materials in OLED device fabrication.
• Cross-Coupling Reactions: The bromine atoms provide excellent handles for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira), enabling rapid diversification of molecular scaffolds.
• Fluorine Chemistry Studies: A valuable substrate for investigating the influence of the difluoromethoxy group on molecular conformation, lipophilicity, and metabolic profile.

Basic Information

Product Name	2,4-Dibromo-3-(difluoromethoxy)benzoic Acid
CAS No.	223595-28-6
Molecular Formula	C8H4Br2F2O3
Molecular Weight	355.92 g/mol
Synonyms	3-(Difluoromethoxy)-2,4-dibromobenzoic Acid; Benzoic acid, 2,4-dibromo-3-(difluoromethoxy)-; 2,4-Dibromo-3-(difluoromethoxy)benzoic acid; 2,4-Dibromo-3-difluoromethoxybenzoic acid
EINECS	Contact for details

Quality Control

Our production of 2,4-Dibromo-3-(difluoromethoxy)benzoic acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The compound may be moisture-sensitive; handle and store under inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.