Description

4-(4-(Trifluoromethyl)Pyridin-2-Yl)Benzoic Acid CAS NO 223127-47-7 is a high-value, multi-functional organic intermediate featuring a benzoic acid core linked to a trifluoromethyl-substituted pyridine ring. This compound is critical for its role in facilitating the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences and specialty chemical sectors for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand Synthesis: Serves as a precursor for chelating ligands in catalysis and material science applications.
• Material Science: Intermediate for the production of advanced organic electronic materials and liquid crystals.
• Chemical Biology: Utilized as a molecular probe or tag in biochemical research due to its distinct structural motif.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-(4-(Trifluoromethyl)Pyridin-2-Yl)Benzoic Acid
CAS No.	223127-47-7
Molecular Formula	C13H8F3NO2
Molecular Weight	267.21 g/mol
Synonyms	2-[4-(Trifluoromethyl)pyridin-2-yl]benzoic acid; 4-(4-Trifluoromethyl-2-pyridinyl)benzoic acid; Benzoic acid, 4-[4-(trifluoromethyl)-2-pyridinyl]-; 4-(4-(Trifluoromethyl)pyridin-2-yl)benzoic acid; 4-(4-Trifluoromethylpyridin-2-yl)benzoic acid; 2-(4-Carboxyphenyl)-4-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our 4-(4-(Trifluoromethyl)Pyridin-2-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.