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(S)-1-[(R)-2-(Di-Tert.-Butylphosphino)Ferrocenyl]Ethyldiphenylphosphine CAS NO 223121-01-5


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CAS No.:223121-01-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(S)-1-[(R)-2-(Di-Tert.-Butylphosphino)Ferrocenyl]Ethyldiphenylphosphine is a highly specialized, chiral ferrocenyl phosphine ligand, a cornerstone in modern asymmetric catalysis. Its value lies in enabling the precise stereochemical control of chemical reactions, which is critical for producing enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-performance ligands for cross-coupling, hydrogenation, and other transition metal-catalyzed transformations.

Application

  • As a chiral ligand in asymmetric hydrogenation reactions for the synthesis of enantiopure pharmaceutical intermediates.
  • Catalyst component for asymmetric cross-coupling reactions (e.g., Suzuki-Miyaura, Heck) in fine chemical production.
  • Key reagent in the development of novel catalytic systems for academic and industrial research in organic synthesis.
  • Used in the synthesis of chiral compounds for agrochemicals and specialty materials.
  • Critical for process chemistry where high enantioselectivity and yield are paramount.

Basic Information

Product Name (S)-1-[(R)-2-(Di-Tert.-Butylphosphino)Ferrocenyl]Ethyldiphenylphosphine
CAS No. 223121-01-5
Molecular Formula C32H40FeP2
Molecular Weight 542.44 g/mol
Synonyms (S,R)-JOSIPHOS; (S)-1-[(R)-2-(Bis(1,1-dimethylethyl)phosphino)ferrocenyl]ethyldiphenylphosphine; Josiphos SL-J009-1; (S)-1-[(R)-2-(Di-tert-butylphosphino)ferrocenyl]ethyldiphenylphosphine; (S)-1-[(R)-2-(Di-tert-butylphosphino)ferrocenyl]ethyl(diphenyl)phosphine; (S)-1-[(R)-2-(Di-tert-butylphosphino)ferrocenyl]ethyl-diphenylphosphine; (1S)-1-[(1R)-2-[Bis(tert-butyl)phosphino]ferrocenyl]ethyldiphenylphosphine
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Quality Control

Every batch of (S)-1-[(R)-2-(Di-Tert.-Butylphosphino)Ferrocenyl]Ethyldiphenylphosphine is manufactured and tested under stringent quality management systems. We ensure compliance with the highest purity standards required for sensitive catalytic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by NMR and HPLC), and chiral purity is provided with each shipment to guarantee batch-to-batch consistency and performance reliability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to prevent oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area separate from incompatible materials.

Specification

Item Specification
Appearance Orange to red powder or crystals
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity (HPLC) ≥ 99.0% ee
Solubility Soluble in common organic solvents (e.g., Toluene, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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