Description

4H-Pyrrolo3,2-Dpyrimidin-4-One, 2-Amino-1,5-Dihydro-7-(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)-2-Pyrrolidinyl-, Monohydrochloride is a high-purity, chemically defined nucleoside analog derivative, essential for advanced pharmaceutical research and development. This compound serves as a critical building block and reference standard in the synthesis of novel antiviral and anticancer therapeutics. It is primarily required by R&D laboratories, process development chemists, and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and analytical method development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies and metabolic pathway investigations.
• Process Development: Serves as a critical raw material for scaling up and optimizing synthetic routes for active pharmaceutical ingredients (APIs).
• Analytical Standard: Employed for method development, validation, and quality control (HPLC, LC-MS) in pharmaceutical analysis.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to design new therapeutic agents.

Basic Information

Item	Details
Product Name	4H-Pyrrolo3,2-Dpyrimidin-4-One, 2-Amino-1,5-Dihydro-7-(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)-2-Pyrrolidinyl-, Monohydrochloride
CAS No.	222631-36-9
Molecular Formula	C11H16ClN5O4
Molecular Weight	317.73 g/mol
Synonyms	2-Amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one hydrochloride; 2-Amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-4-one hydrochloride; 2-Amino-7-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-4-one HCl; Nucleoside analog derivative; Pyrrolopyrimidine nucleoside HCl salt
EINECS	Contact for details

Quality Control

Our 4H-Pyrrolo3,2-Dpyrimidin-4-One derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.