Description

1,3-Isobenzofurandione,5-(Bromomethyl)-(9Ci) is a specialized brominated phthalic anhydride derivative, serving as a key synthetic intermediate for advanced organic transformations. Its core value lies in introducing both a reactive bromomethyl group and an anhydride functionality into target molecules, enabling the construction of complex heterocyclic and polymer architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for drug discovery, crop protection agents, and specialty polymers.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in developing kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, where the bromomethyl group facilitates key coupling reactions.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating high-performance polymers, including polyimides, epoxy resins, and flame-retardant materials.
• Ligand & Catalyst Development: Employed in the design and synthesis of complex organic ligands for catalysis and metal-organic frameworks (MOFs).
• Dye & Pigment Manufacturing: Acts as a precursor for synthesizing specialized phthalocyanine dyes and organic pigments.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in organic synthesis and methodology development.

Basic Information

Product Name	1,3-Isobenzofurandione,5-(Bromomethyl)-(9Ci)
CAS No.	222549-72-6
Molecular Formula	C9H5BrO3
Molecular Weight	241.04 g/mol
Synonyms	5-(Bromomethyl)isobenzofuran-1,3-dione; 5-(Bromomethyl)phthalic anhydride; 1,3-Dioxoisobenzofuran-5-ylmethyl bromide; 5-Bromomethylphthalic anhydride; Bromomethylphthalic anhydride; 222549-72-6; (9CI) 1,3-Isobenzofurandione, 5-(bromomethyl)-
EINECS	Contact for details

Quality Control

Our 1,3-Isobenzofurandione,5-(Bromomethyl)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 96.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.