Description

(3-Bromo-2,6-Dimethoxy-4-Pyridyl)Diphenylphosphine Oxide is a high-value organophosphorus compound featuring a halogenated pyridine core, making it a versatile and highly sought-after intermediate in advanced chemical synthesis. Its unique structure, combining a phosphine oxide moiety with bromine and methoxy substituents, provides exceptional utility in cross-coupling reactions and as a ligand precursor. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and materials science industries who require sophisticated building blocks for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological disorders and oncology.
• Ligand Synthesis: Serves as a precursor for the development of specialized phosphine ligands used in homogeneous catalysis, such as palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Agrochemical Research: Used in the creation of novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Employed in the development of organic electronic materials, including OLEDs and conductive polymers, due to its electron-accepting properties.
• Chemical Synthesis: Acts as a versatile reagent for introducing the (diphenylphosphinoyl)pyridyl moiety into more complex molecular architectures.
• Academic & Industrial R&D: A critical reagent for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Item	Detail
Product Name	(3-Bromo-2,6-Dimethoxy-4-Pyridyl)Diphenylphosphine Oxide
CAS No.	220998-36-7
Molecular Formula	C19H17BrNO3P
Molecular Weight	418.22 g/mol
Synonyms	4-(Diphenylphosphinyl)-3-bromo-2,6-dimethoxypyridine; (3-Bromo-2,6-dimethoxy-4-pyridinyl)diphenylphosphine oxide; Diphenyl(3-bromo-2,6-dimethoxy-4-pyridyl)phosphine oxide; 3-Bromo-2,6-dimethoxy-4-pyridyldiphenylphosphine oxide; 4-(Diphenylphosphoryl)-3-bromo-2,6-dimethoxypyridine; BRD-DPPO (abbrev.); Bromo-dimethoxypyridyl phosphine oxide
EINECS	Contact for details

Quality Control

Our production of (3-Bromo-2,6-Dimethoxy-4-Pyridyl)Diphenylphosphine Oxide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including NMR, HPLC, and elemental analysis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support cGMP and ISO 9001 standards for research and development materials, ensuring traceability and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed in a desiccator to minimize exposure to atmospheric moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.