Description

4-(3-Methyl-1H-Pyrazol-1-Yl)-2-Trifluoromethylbenzoic Acid is a high-purity, functionalized benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring a pyrazole ring and a trifluoromethyl group, makes it a valuable intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in oncology, anti-inflammatory, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for designing specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its aromatic and heterocyclic structure.
• Chemical Biology Probes: Useful for constructing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	4-(3-Methyl-1H-Pyrazol-1-Yl)-2-Trifluoromethylbenzoic Acid
CAS No.	220462-01-1
Molecular Formula	C12H9F3N2O2
Molecular Weight	270.21 g/mol
Synonyms	2-Trifluoromethyl-4-(3-methyl-1H-pyrazol-1-yl)benzoic Acid; 4-(3-Methylpyrazol-1-yl)-2-trifluoromethylbenzoic Acid; 1-[4-Carboxy-3-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazole; Benzoic acid, 4-(3-methyl-1H-pyrazol-1-yl)-2-(trifluoromethyl)-; 220462-01-1; 4-(3-Methyl-1H-pyrazol-1-yl)-α,α,α-trifluoro-o-toluic acid
EINECS	Contact for details

Quality Control

Our production of 4-(3-Methyl-1H-Pyrazol-1-Yl)-2-Trifluoromethylbenzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Our quality systems are designed to support customer requirements for research, development, and scale-up activities under ISO-guided standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.