Description

Escitalopram Oxalate is the oxalate salt form of the selective serotonin reuptake inhibitor (SSRI) escitalopram, a key active pharmaceutical ingredient (API). This high-purity compound is essential for the formulation of antidepressant medications, offering critical therapeutic efficacy and stability. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of central nervous system (CNS) drugs and generic pharmaceuticals.

Application

• Active Pharmaceutical Ingredient (API): Primary use in the manufacture of antidepressant tablets, capsules, and oral solutions.
• Pharmaceutical Research & Development: Serves as a reference standard and key intermediate in preclinical and clinical studies for mood disorder treatments.
• Generic Drug Formulation: Critical for companies developing bioequivalent versions of branded SSRI medications.
• Analytical Testing: Used as a certified reference material (CRM) in quality control laboratories for HPLC and spectroscopic assays.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for finished dosage form production.

Basic Information

Product Name	Escitalopram Oxalate
CAS No.	219861-08-2
Molecular Formula	C22H23FN2O • C2H2O4
Molecular Weight	450.44 g/mol
Synonyms	S-Citalopram Oxalate; (S)-Citalopram Oxalate; Escitalopram Hydrogen Oxalate; Lexapro® API; Lu-26-054; 1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile oxalate; (S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate
EINECS	Contact for details

Quality Control

Our Escitalopram Oxalate is manufactured under strict quality systems, targeting compliance with ICH Q7 guidelines and relevant pharmacopoeial standards (e.g., USP, EP). Every batch undergoes comprehensive analytical testing, including identity, purity, and impurity profile determination. A Certificate of Analysis (COA) documenting all test results is provided to ensure full traceability and regulatory support for your projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: NMT 0.15% Total impurities: NMT 0.5%
Water Content (KF)	NMT 1.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.