Description

4-Fluorophenyl 3-(Trifluoromethyl)Benzoate is a high-value fluorinated aromatic ester building block, distinguished by its unique combination of fluorine and trifluoromethyl substituents. This compound is critical for introducing lipophilicity and metabolic stability into target molecules, making it a sought-after intermediate in advanced chemical synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine motifs enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Acts as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Organic Electronics: Employed in the development of organic semiconductors and charge-transport materials due to its electron-withdrawing properties.
• Chemical Research: A versatile building block for Suzuki-Miyaura and other cross-coupling reactions to create complex, polyfluorinated biaryl systems.
• Polymer Modification: Used to incorporate fluorinated aromatic units into specialty polymers to alter thermal stability and surface properties.

Basic Information

Product Name	4-Fluorophenyl 3-(Trifluoromethyl)Benzoate
CAS No.	218929-27-2
Molecular Formula	C14H8F4O2
Molecular Weight	284.21 g/mol
Synonyms	3-(Trifluoromethyl)benzoic acid 4-fluorophenyl ester; 4-Fluorophenyl 3-(trifluoromethyl)benzoate; Benzoic acid, 3-(trifluoromethyl)-, 4-fluorophenyl ester; 4-Fluorophenyl m-trifluoromethylbenzoate; [4-Fluorophenyl] 3-(trifluoromethyl)benzoate; 4-Fluorophenyl α,α,α-trifluoro-m-toluate
EINECS	Contact for details

Quality Control

Our 4-Fluorophenyl 3-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures material consistency and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.