Description

1H-Indene-1,2-Diamine,2,3-Dihydro-,(1S,2R)-(9Ci) CAS NO 218151-56-5 is a high-purity, chiral diamine derivative of indene, serving as a sophisticated building block in advanced organic synthesis. Its defined stereochemistry and rigid, fused-ring structure make it a critical intermediate for constructing complex molecules with specific three-dimensional architectures. This compound is essential for research and development in the pharmaceutical and agrochemical sectors, where it is utilized to create novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Asymmetric Catalyst Ligand: Used in the synthesis of chiral ligands for transition metal catalysts, enabling enantioselective transformations in fine chemical production.
• Agrochemical Research: Serves as a building block for creating new chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Material Science: Investigated as a monomer or cross-linking agent for the synthesis of specialty polymers with unique thermal or optical properties.
• Academic & R&D: Employed in university and industrial research laboratories for methodological studies in organic synthesis and stereochemistry.

Basic Information

Product Name	1H-Indene-1,2-Diamine,2,3-Dihydro-,(1S,2R)-(9Ci)
CAS No.	218151-56-5
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	(1S,2R)-1,2-Diamino-2,3-dihydro-1H-indene; (1S,2R)-1,2-Diaminoindane; (1S,2R)-Indane-1,2-diamine; (1S,2R)-1,2-Diamino-1,2,3,4-tetrahydro-1H-indene; (1S,2R)-1,2-Dihydro-1H-indene-1,2-diamine; cis-1,2-Diaminoindane (specific enantiomer); Chiral Indane Diamine
EINECS	Contact for details

Quality Control

Our 1H-Indene-1,2-Diamine,2,3-Dihydro-,(1S,2R)-(9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the exacting standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1S,2R)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.