Description

6-Bromo-2-Fluoro-3-Iodobenzoic Acid is a highly functionalized benzoic acid derivative, serving as a critical multi-halogenated building block in advanced organic synthesis. Its unique halogen pattern (Br, F, I) offers distinct reactivity and electronic properties, enabling precise molecular construction. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting CNS disorders and oncology.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the halogen atoms for bioactivity and metabolic stability.
• Material Science: Used in the creation of specialty polymers, liquid crystals, and organic electronic materials where halogen atoms tune electronic properties.
• Cross-Coupling Reactions: The iodine and bromine substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Derivatization Studies: The carboxylic acid group allows for easy conversion to amides, esters, and other derivatives for structure-activity relationship (SAR) studies.
• Chemical Biology Probes: Serves as a starting point for synthesizing molecular probes and tags used in biochemical and diagnostic research.

Basic Information

Product Name	6-Bromo-2-Fluoro-3-Iodobenzoic Acid
CAS No.	217816-53-0
Molecular Formula	C7H3BrFIO2
Molecular Weight	354.90 g/mol
Synonyms	3-Iodo-6-bromo-2-fluorobenzoic Acid; 2-Fluoro-3-iodo-6-bromobenzoic Acid; Benzoic acid, 6-bromo-2-fluoro-3-iodo-; 6-Bromo-2-fluoro-3-iodobenzoic acid; 217816-53-0; 6-Br-2-F-3-I-BA
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Fluoro-3-Iodobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.