Description

Paroxetine Mesylate CAS NO 217797-14-3 is the mesylate salt form of paroxetine, a potent and selective serotonin reuptake inhibitor (SSRI). This salt form is crucial for enhancing the stability, solubility, and bioavailability of the active pharmaceutical ingredient (API) for formulation. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development and production of antidepressant medications. The compound's high purity and consistent quality are essential for ensuring the efficacy and safety of the final drug product.

Application

• Active Pharmaceutical Ingredient (API): Primary use as the key therapeutic component in the manufacture of antidepressant drugs.
• Pharmaceutical Intermediates: Serves as a critical intermediate in the synthesis of final paroxetine-based dosage forms.
• Reference Standard: Used in analytical laboratories for quality control, method development, and validation in pharmaceutical testing.
• Clinical Research: Employed in preclinical and clinical studies for the development of new neuropsychiatric therapies.
• Generic Drug Manufacturing: Essential for companies producing generic versions of paroxetine medications.
• Formulation Development: Used in R&D to study and optimize drug delivery systems, such as tablets or capsules.

Basic Information

Product Name	Paroxetine Mesylate
CAS No.	217797-14-3
Molecular Formula	C19H20FNO3 • CH4O3S
Molecular Weight	425.48 g/mol
Synonyms	Paroxetine methanesulfonate; (-)-trans-4-(4'-Fluorophenyl)-3-[(3',4'-methylenedioxy)phenoxy]methylpiperidine methanesulfonate; (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine methanesulfonate; Paroxetine mesilate; BRL-29060 mesylate; Aropax mesylate; Paxil mesylate; Seroxat mesylate
EINECS	Contact for details

Quality Control

Our Paroxetine Mesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide full traceability and support with regulatory documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.