Description

Abacavir Sulfate is the sulfate salt form of a potent nucleoside reverse transcriptase inhibitor (NRTI). This active pharmaceutical ingredient (API) is critical for the formulation of antiretroviral therapies targeting HIV-1 infection. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of antiviral medications. The compound is supplied under stringent quality controls to ensure efficacy and safety in final drug products.

Application

• Pharmaceutical API: Primary use as the active ingredient in antiretroviral combination therapies for the treatment of HIV-1.
• Fixed-Dose Combination Drugs: Formulation into combination tablets with other antiretroviral agents like lamivudine and zidovudine.
• Pediatric Formulations: Development of oral solutions and scored tablets for pediatric HIV treatment regimens.
• Clinical Research: Use as a reference standard and raw material in preclinical and clinical studies for new HIV therapies.
• Generic Drug Manufacturing: Sourcing for the production of bioequivalent generic antiviral medications.
• Analytical Testing: Serves as a high-purity standard for quality control and assay development in analytical laboratories.

Basic Information

Product Name	Abacavir Sulfate
CAS No.	216699-07-9
Molecular Formula	C14H20N6O5 • H2SO4
Molecular Weight	670.76 g/mol
Synonyms	Abacavir Sulphate; (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol sulfate; Ziagen (Brand Name); ABC Sulfate; Abacavir (as sulfate); 1592U89 Sulfate; Cyclopropavir Sulfate; NSC-725403 (Sulfate)
EINECS	Contact for details

Quality Control

Our Abacavir Sulfate is manufactured and tested to meet the stringent requirements of major pharmacopoeias, including USP and EP monographs. Every batch undergoes comprehensive analytical testing for identity, purity, potency, and specified impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications and current Good Manufacturing Practice (cGMP) standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. The original container should be kept tightly sealed after each use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5%; Total impurities: ≤ 1.5%
Specific Rotation	Contact for details
Microbial Limits	Conforms to USP/EP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.