Description

4-Bromo-2-Fluorobenzeneboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key synthon for creating novel active pharmaceutical ingredients (APIs), especially in drug discovery for oncology and CNS diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts.
• Material Science Research: Building block for organic electronic materials, such as OLEDs and semiconductors, where specific halogen/fluorine patterns are required.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for diagnostic and imaging applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving diverse R&D and scale-up projects.

Basic Information

Product Name	4-Bromo-2-Fluorobenzeneboronic Acid
CAS No.	216393-64-5
Molecular Formula	C6H5BBrFO2
Molecular Weight	218.82 g/mol
Synonyms	(4-Bromo-2-fluorophenyl)boronic acid; 2-Fluoro-4-bromobenzeneboronic acid; 4-Bromo-2-fluorophenylboronic acid; B-(4-Bromo-2-fluorophenyl)boronic acid; 216393-64-5; 4-Bromo-2-fluoro-benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorobenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance in cross-coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.