Description

R-3,3'-Bis([1,1'-Biphenyl]-4-Yl)-1,1'-Binaphthalene]-2,2'-Diol is a sophisticated chiral binaphthol derivative, a high-value organic intermediate prized for its rigid, axially chiral scaffold. This compound is critical for constructing advanced asymmetric catalysts and chiral ligands, enabling highly selective chemical transformations in fine chemical synthesis. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Catalysis: Serves as a privileged precursor for synthesizing chiral phosphine, phosphoramidite, and N-heterocyclic carbene (NHC) ligands used in cross-coupling, hydrogenation, and other enantioselective reactions.
• Pharmaceutical Intermediates: Key building block in the research and development of active pharmaceutical ingredients (APIs) where chirality is crucial for biological activity.
• Material Science: Used in the development of chiral organic frameworks, liquid crystals, and polymers with specific optical or electronic properties.
• Agrochemical Synthesis: Employed in creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A vital tool for chemists exploring new methodologies in stereoselective synthesis and organometallic chemistry.

Basic Information

Product Name	R-3,3'-Bis([1,1'-Biphenyl]-4-Yl)-1,1'-Binaphthalene]-2,2'-Diol
CAS No.	215433-52-6
Molecular Formula	C48H30O2
Molecular Weight	638.75 g/mol
Synonyms	(R)-3,3'-Bis(4-biphenylyl)-1,1'-bi-2-naphthol; (R)-3,3'-Bis([1,1'-biphenyl]-4-yl)-1,1'-binaphthalene-2,2'-diol; (R)-3,3'-Bis(4-phenylphenyl)-[1,1'-binaphthalene]-2,2'-diol; R-BINOL-Biph Derivative; R-3,3'-Di([1,1'-biphenyl]-4-yl)-BINOL; (R)-BINOL-3,3'-dibiphenyl; (R)-3,3'-Bis(4-biphenylyl)-BINOL
EINECS	Contact for details

Quality Control

Our production of this high-purity chiral compound adheres to stringent quality assurance protocols. Every batch is characterized and tested to ensure identity, purity, and enantiomeric excess meet exacting standards. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results from chiral HPLC, NMR, and other analytical methods. We support cGMP and ISO 9001 compliant manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and enantiomeric purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.