Description

R-3-3'-Bis(3,5-Bis(Methyl)Phenyl)-1,1'-Bi-2-Naphthol is a high-value, axially chiral binaphthol derivative, serving as a sophisticated ligand and catalyst precursor in asymmetric synthesis. Its core value lies in enabling highly enantioselective transformations, which are critical for producing single-isomer pharmaceuticals and fine chemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• As a chiral ligand for transition metal catalysts in asymmetric hydrogenation, C-C bond formation, and oxidation reactions.
• As a key building block for constructing chiral organocatalysts used in pharmaceutical intermediate synthesis.
• In the development of chiral stationary phases (CSPs) for analytical and preparative-scale chromatographic separation of enantiomers.
• For research into novel chiral materials with potential applications in organic electronics and nonlinear optics.
• As a precursor for chiral phosphoric acid catalysts used in Mannich, Friedel-Crafts, and other carbon-heteroatom bond-forming reactions.
• In methodological studies to develop new catalytic asymmetric processes in academic and industrial R&D laboratories.

Basic Information

Item	Detail
Product Name	R-3-3'-Bis(3,5-Bis(Methyl)Phenyl)-1,1'-Bi-2-Naphthol
CAS No.	215433-51-5
Molecular Formula	C40H34O2
Molecular Weight	546.70 g/mol
Synonyms	(R)-3,3'-Bis(3,5-dimethylphenyl)-1,1'-bi-2-naphthol; (R)-3,3'-Bis(3,5-dimethylphenyl)-BINOL; (R)-3,3'-Di(3,5-xylyl)-BINOL; (R)-3,3'-Bis(3,5-dimethylphenyl)-[1,1'-binaphthalene]-2,2'-diol; R-DM-BINOL; (R)-3,3'-Dixylyl-BINOL; (R)-3,3'-Bis(3,5-dimethylphenyl)-H8-BINOL (common misnomer); R-3,3'-Ar-BINOL derivative
EINECS	Contact for details

Quality Control

Every batch of our R-3-3'-Bis(3,5-Bis(Methyl)Phenyl)-1,1'-Bi-2-Naphthol is produced and tested under strict quality management systems. We ensure high enantiomeric excess (ee) and chemical purity through advanced analytical techniques including HPLC, chiral HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and residual solvent content is provided with each shipment to guarantee batch-to-batch consistency and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere to prevent potential oxidation and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.