Description

Fmoc-D-Phenylglycinol CAS NO 215178-43-1 is a high-purity, chiral amino alcohol derivative protected with a 9-fluorenylmethoxycarbonyl (Fmoc) group. This compound serves as a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules and bioactive peptides. It is essential for research and production in pharmaceutical development, asymmetric synthesis, and advanced material science, where precise stereochemistry is paramount for biological activity and product efficacy.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and neurological drug candidates.
• Peptide Synthesis: Used as a protected amino alcohol building block in solid-phase and solution-phase peptide synthesis (SPPS) to introduce the D-phenylglycinol moiety.
• Asymmetric Catalysis & Ligand Synthesis: Employed in the preparation of chiral ligands, catalysts, and auxiliaries for enantioselective transformations.
• Proteomics & Biochemical Research: Utilized in the study of enzyme inhibitors, receptor binding studies, and the development of molecular probes.
• Material Science: Acts as a monomer or precursor for chiral polymers and advanced functional materials with specific optical properties.

Basic Information

Product Name	Fmoc-D-Phenylglycinol
CAS No.	215178-43-1
Molecular Formula	C22H19NO3
Molecular Weight	345.39 g/mol
Synonyms	(R)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-phenylethanol; D-Fmoc-Phenylglycinol; Fmoc-D-Phg-ol; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-phenylglycinol; (R)-N-Fmoc-2-amino-2-phenylethanol; (R)-2-(Fmoc-amino)-2-phenylethanol; Fmoc-D-β-phenylalaninol; Fmoc-D-Phenylglycine alcohol
EINECS	Contact for details

Quality Control

Our Fmoc-D-Phenylglycinol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and cGMP-grade production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.