Description

Boc-Dap(Dnp)-Osu is a specialized, protected amino acid derivative widely used as a key building block in peptide synthesis. This compound is critical for researchers and manufacturers requiring high-purity intermediates for the development of complex peptides and peptide-based pharmaceuticals. It is primarily utilized in the pharmaceutical, biotechnology, and advanced life science research sectors for constructing specific peptide sequences with precision.

Application

• Solid-Phase Peptide Synthesis (SPPS): A crucial reagent for the controlled, sequential addition of amino acids, particularly where the side-chain protection of aspartic acid is required.
• Solution-Phase Peptide Synthesis: Employed in the synthesis of peptide fragments and small peptides in solution, offering flexibility in complex synthetic routes.
• Pharmaceutical Intermediate: Serves as a key intermediate in the research and development of novel therapeutic peptides and peptidomimetics.
• Bioconjugation Chemistry: Used in the modification of proteins, antibodies, or other biomolecules by introducing specific functional groups via its active ester moiety.
• Chemical Biology Research: A valuable tool for studying protein-protein interactions, enzyme mechanisms, and for creating custom peptide probes and inhibitors.
• Production of Custom Peptides: Essential for contract research organizations (CROs) and manufacturers producing bespoke peptides for research and diagnostic applications.

Basic Information

Product Name	Boc-Dap(Dnp)-Osu
CAS No.	214750-68-2
Molecular Formula	C19H24N4O10
Molecular Weight	468.42 g/mol
Synonyms	N-α-(tert-Butoxycarbonyl)-N-β-(2,4-dinitrophenyl)-L-asparagine N-hydroxysuccinimide ester; Boc-Asp(Dnp)-OSu; Boc-L-Asparagine(Dnp)-OSu; (2S)-2-[(tert-Butoxycarbonyl)amino]-3-[(2,4-dinitrophenyl)amino]-3-oxopropyl 2,5-dioxopyrrolidin-1-yl ester; tert-Butyl ((1S)-1-((2,4-dinitrophenyl)amino)-3-((2,5-dioxopyrrolidin-1-yl)oxy)-1-oxopropan-2-yl)carbamate; Boc-Asp(2,4-Dnp)-OSu; Boc-D-Asp(Dnp)-OSu (for D-isomer); L-Asparagine, N2-[(1,1-dimethylethoxy)carbonyl]-N3-(2,4-dinitrophenyl)-, 1-(2,5-dioxo-1-pyrrolidinyl) ester
EINECS	Contact for details

Quality Control

Our Boc-Dap(Dnp)-Osu is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.