Description

Efalizumabum CAS NO 214745-43-4 is a recombinant humanized monoclonal antibody designed to target specific immune cell surface proteins. This compound is of significant interest for its targeted mechanism of action in modulating immune responses. It is primarily required by pharmaceutical research and development organizations, biotechnology companies, and advanced therapeutic manufacturers engaged in immunology and autoimmune disease research.

Application

• Primary active pharmaceutical ingredient (API) in targeted biologic therapies.
• Key reagent in preclinical and clinical research for autoimmune and inflammatory conditions.
• Critical component in the development of biosimilar and novel biologic entities.
• Used in immunological assays and diagnostic development for specific cell surface marker detection.
• Reference standard for quality control and analytical method validation in biopharmaceutical production.
• Fundamental material for structure-activity relationship (SAR) studies in immunology.

Basic Information

Product Name	Efalizumabum
CAS No.	214745-43-4
Molecular Formula	C~6420~H~9912~N~1696~O~2016~S~44~
Molecular Weight	Approx. 150 kDa
Synonyms	Efalizumab; Raptiva; Anti-LFA-1; Anti-CD11a; hu1124; Recombinant Humanized Anti-CD11a Monoclonal Antibody; LFA-3/IgG1 Fusion Protein; Xanelim
EINECS	Contact for details

Quality Control

Our Efalizumabum is manufactured under strict quality systems. Each batch is subjected to a comprehensive suite of analytical tests including identity confirmation, purity assessment, potency testing, and impurity profiling to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) documenting purity, biological activity, endotoxin levels, and other critical quality attributes are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive) and must be handled in a controlled, low-humidity environment.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 95.0% (Monomer)
Assay (ELISA/Bioassay)	90.0% - 110.0% of labeled potency
Protein Content	≥ 95.0% (by UV)
Endotoxin	< 1.0 EU/mg
Host Cell Proteins	< 100 ppm
Residual DNA	< 10 pg/mg
Sterility (where applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.