Description

(S)-2-Chlorophenylglycinol is a high-value chiral building block and intermediate of significant importance in asymmetric synthesis. Its primary value lies in its utility for constructing complex molecules, particularly in the pharmaceutical sector where enantiomeric purity is critical. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in neurologically active compounds and receptor antagonists.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Intermediate in the production of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Building Block: Employed in the research and development of complex organic molecules requiring high stereochemical fidelity.
• Academic & R&D Laboratories: Serves as a standard or starting material for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(S)-2-Chlorophenylglycinol
CAS No.	213990-63-7
Molecular Formula	C8H10ClNO
Molecular Weight	171.62 g/mol
Synonyms	(S)-2-Amino-1-(2-chlorophenyl)ethanol; (S)-1-(2-Chlorophenyl)-2-aminoethanol; (S)-2-Chloro-α-(aminomethyl)benzyl alcohol; (S)-(-)-2-Chlorophenylglycinol; (1S)-2-Amino-1-(2-chlorophenyl)ethan-1-ol; (S)-2-Chloro-α-aminobenzyl alcohol; (S)-α-(Aminomethyl)-2-chlorobenzyl alcohol
EINECS	Contact for details

Quality Control

Our (S)-2-Chlorophenylglycinol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with full batch traceability are provided.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.