Description

4-(Trifluorovinyloxyphenyl)Boronic Acid is a specialized organoboron compound featuring a unique trifluorovinyloxy phenyl backbone. This high-value intermediate is critical for advanced cross-coupling reactions, particularly in the synthesis of complex fluorinated molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel chemical entities.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for creating biaryl and heterobiaryl structures with fluorinated side chains, essential in medicinal chemistry.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), especially those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides, fungicides, and insecticides where the fluorine moiety improves efficacy and environmental profile.
• Advanced Material Development: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic electronic materials for specialized performance characteristics.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating compound libraries for high-throughput screening.

Basic Information

Product Name	4-(Trifluorovinyloxyphenyl)Boronic Acid
CAS No.	213701-14-5
Molecular Formula	C8H6BF3O3
Molecular Weight	217.94 g/mol
Synonyms	4-(Trifluorovinyloxy)benzeneboronic Acid; [4-(Trifluorovinyloxy)phenyl]boronic Acid; 4-(Trifluorovinyloxy)phenylboronic Acid; 4-(1,2,2-Trifluorovinyloxy)benzeneboronic Acid; 4-(Trifluorovinyloxy)phenyl-B(OH)2; Boronic acid, B-[4-[(1,2,2-trifluoroethenyl)oxy]phenyl]-; 4-(Perfluorovinyloxy)phenylboronic Acid (common name variant)
EINECS	Contact for details

Quality Control

Our 4-(Trifluorovinyloxyphenyl)Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including NMR (¹H, ¹³C, ¹⁹F), HPLC, and Karl Fischer titration to confirm identity, purity, and moisture content. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF Titration)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.