Description

4-Ethyl-3-Trifluoromethylbenzoic Acid is a high-value fluorinated aromatic building block characterized by its benzoic acid core substituted with both ethyl and trifluoromethyl groups. This compound matters for its unique combination of lipophilicity and electronic properties imparted by the fluorine atoms, making it a critical intermediate in advanced synthesis. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Liquid Crystal Materials: Acts as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the development of organic semiconductors and other electronic materials due to its electron-withdrawing properties.
• Advanced Polymer Modification: Utilized to introduce fluorine-containing side chains into polymers to alter surface properties, chemical resistance, and stability.
• Chemical Research & Development: A versatile building block for medicinal chemistry and material science research, enabling structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Ethyl-3-Trifluoromethylbenzoic Acid
CAS No.	213598-17-5
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	3-(Trifluoromethyl)-4-ethylbenzoic Acid; 4-Ethyl-α,α,α-trifluoro-m-toluic Acid; Benzoic acid, 4-ethyl-3-(trifluoromethyl)-; 4-Ethyl-3-trifluoromethylbenzoic acid; 4-Ethyl-α,α,α-trifluoro-m-toluic acid; m-Toluic acid, 4-ethyl-α,α,α-trifluoro-
EINECS	Contact for details

Quality Control

Our 4-Ethyl-3-Trifluoromethylbenzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.