Description

Eniporide Hydrochloride is a high-purity, small molecule pharmaceutical intermediate and research chemical. This compound is a potent and selective inhibitor of the sodium-hydrogen exchanger isoform 1 (NHE-1), making it a critical tool in cardiovascular and ischemia-reperfusion injury research. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and fine chemical manufacturers for developing novel therapeutic agents and conducting preclinical studies.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel cardioprotective drugs targeting myocardial infarction and heart failure.
• Preclinical Studies: For investigating the role of the NHE-1 transporter in cellular injury models related to ischemia, stroke, and cardiac hypertrophy.
• Biochemical Assay Development: Used as a reference standard and active control in high-throughput screening (HTS) assays to discover new NHE-1 inhibitors.
• Academic Research: A vital reagent for university and institutional labs studying ion transport mechanisms, cellular pH regulation, and related pathophysiology.
• Fine Chemical Synthesis: Serves as a building block for the custom synthesis of more complex, targeted molecules for specialized research programs.

Basic Information

Product Name	Eniporide Hydrochloride
CAS No.	211813-86-4
Molecular Formula	C15H21N3O3S • HCl
Molecular Weight	359.87 g/mol (as hydrochloride salt)
Synonyms	4-Isopropyl-3-methylsulfonylbenzoylguanidine methanesulfonate hydrochloride; BIIB 513; Eniporide HCl; NHE-1 Inhibitor BIIB 513; (4-Isopropyl-3-methylsulfonylbenzoyl)guanidine methanesulfonate hydrochloride; 1-(4-Isopropyl-3-methylsulfonylbenzoyl)guanidine methanesulfonate hydrochloride
EINECS	Contact for details

Quality Control

Our Eniporide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain purity and potency. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤20 ppm
Single Unknown Impurity	≤0.5%
Total Impurities	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.