Description

4-Bromo-2,6-Bis(trifluoromethyl)benzoic acid is a highly functionalized aromatic building block characterized by its electron-deficient benzoic acid core substituted with bromine and two trifluoromethyl groups. This compound matters for its role as a key intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique steric and electronic properties are leveraged. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl groups contribute to lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands used in transition metal catalysis, benefiting from the steric bulk of the substituents.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as semiconductors or liquid crystals, where fluorination tunes electronic properties.
• Custom Synthesis and Contract Manufacturing: A valuable scaffold for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	4-Bromo-2,6-Bis(trifluoromethyl)benzoic Acid
CAS No.	210491-38-6
Molecular Formula	C9H3BrF6O2
Molecular Weight	337.02 g/mol
Synonyms	4-Bromo-2,6-bis(trifluoromethyl)benzoic acid; 2,6-Bis(trifluoromethyl)-4-bromobenzoic acid; Benzoic acid, 4-bromo-2,6-bis(trifluoromethyl)-; 4-Bromo-α,α,α,α',α',α'-hexafluoromesitylenecarboxylic acid; 4-Bromo-2,6-di(trifluoromethyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,6-Bis(trifluoromethyl)benzoic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.