Description

Ethyl 2-Fluoro-6-Hydroxybenzoate is a versatile fluorinated aromatic ester building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a phenolic hydroxyl group and an ethyl ester, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those requiring a fluorinated benzoate scaffold for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the fluorine atom and phenolic moiety contribute to biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic cores in electronic materials, influencing dielectric anisotropy and emission properties.
• Polymer Modification: Employed to introduce fluorinated phenolic groups into polymer chains, altering surface properties, chemical resistance, and thermal stability.
• Organic Synthesis Reagent: A valuable starting material for further derivatization, including etherification, hydrolysis, and cross-coupling reactions to create diverse chemical libraries.
• Flavor & Fragrance Intermediate: Potential use in the synthesis of complex aromatic esters for specialty fragrance and flavor applications.

Basic Information

Product Name	Ethyl 2-Fluoro-6-Hydroxybenzoate
CAS No.	208708-03-6
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	2-Fluoro-6-hydroxybenzoic acid ethyl ester; Ethyl 2-fluoro-6-hydroxybenzoate; Benzoic acid, 2-fluoro-6-hydroxy-, ethyl ester; 6-Hydroxy-2-fluorobenzoic Acid Ethyl Ester; 2-Fluoro-6-hydroxy-benzoic acid ethyl ester; Ethyl 6-hydroxy-2-fluorobenzoate; 208708-03-6; Ethyl 2-fluoro-6-hydroxybenzenecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Fluoro-6-Hydroxybenzoate is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for fine chemical and pharmaceutical-grade intermediates. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.