Description

(1R,2R)-4-Cyclohexene-1,2-Diamine is a high-purity, chiral diamine building block of significant importance in asymmetric synthesis. Its rigid cyclohexene backbone and specific stereochemistry make it a valuable precursor for creating chiral ligands, catalysts, and complex pharmaceutical intermediates. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce precise stereocenters into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug candidates.
• Chiral Ligand & Catalyst Synthesis: Serves as a core structure for developing novel chiral ligands used in asymmetric hydrogenation, epoxidation, and other enantioselective catalytic reactions.
• Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Synthesis: Employed in the preparation of specialty chemicals, flavors, and fragrances where stereochemical control is critical.
• Polymer Modification: Can be utilized as a cross-linking agent or monomer to introduce rigidity and specific functionality into polymer chains.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	(1R,2R)-4-Cyclohexene-1,2-Diamine
CAS No.	208533-40-8
Molecular Formula	C6H12N2
Molecular Weight	112.17 g/mol
Synonyms	(1R,2R)-1,2-Diaminocyclohex-4-ene; (1R,2R)-4-Cyclohexene-1,2-diamine; (1R,2R)-1,2-Diamino-4-cyclohexene; (1R,2R)-Cyclohex-4-ene-1,2-diamine; (1R,2R)-1,2-Diaminocyclohex-4-ene; (1R,2R)-1,2-DACH; (1R,2R)-DACH; (1R,2R)-trans-1,2-Diaminocyclohex-4-ene
EINECS	Contact for details

Quality Control

Our (1R,2R)-4-Cyclohexene-1,2-Diamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.