Description

2,3-Difluorocinnamic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its role in introducing the difluorophenyl moiety into target molecules, enabling the fine-tuning of physicochemical properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting CNS disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Organic Electronic Materials: Employed in the development of organic semiconductors and electro-optical materials due to its electron-withdrawing characteristics.
• Chemical Research: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to create complex, fluorinated biaryl structures.
• Fluorine Chemistry Studies: Used as a standard or model compound in academic and industrial research exploring the effects of fluorine substitution on reaction pathways.

Basic Information

Item	Details
Product Name	2,3-Difluorocinnamic Acid
CAS No.	207981-48-4
Molecular Formula	C9H6F2O2
Molecular Weight	184.14 g/mol
Synonyms	(2E)-3-(2,3-Difluorophenyl)prop-2-enoic acid; trans-2,3-Difluorocinnamic Acid; (E)-3-(2,3-Difluorophenyl)acrylic acid; 2,3-Difluorocinnameic Acid; 2,3-DFCA; 3-(2,3-Difluorophenyl)-2-propenoic Acid
EINECS	Contact for details

Quality Control

Our 2,3-Difluorocinnamic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.