Description

1-[(2S,3S,4S,5S)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-1,2,4-Triazole-3-Carboxamide is a high-purity nucleoside analogue with significant potential in advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate or active pharmaceutical ingredient (API) in the creation of novel antiviral and anticancer therapeutics. It is primarily sought by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the synthesis of next-generation nucleoside-based drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer nucleoside analogues.
• Biochemical Research: Used as a reference standard or probe in enzymatic studies and metabolic pathway research.
• Antiviral Drug Development: Investigated for its potential activity against a range of viral targets due to its modified nucleoside structure.
• Oncology Research: Explored in preclinical studies for its mechanism of action in disrupting DNA/RNA synthesis in cancer cells.
• Process Chemistry: Employed in scale-up and optimization studies for the production of related active pharmaceutical ingredients (APIs).
• Academic Synthesis: Used in university laboratories for teaching and research in advanced organic and medicinal chemistry.

Basic Information

Product Name	1-[(2S,3S,4S,5S)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-1,2,4-Triazole-3-Carboxamide
CAS No.	206269-27-4
Molecular Formula	C9H13N5O5
Molecular Weight	271.23 g/mol
Synonyms	1-(β-D-Ribofuranosyl)-1,2,4-triazole-3-carboxamide; 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide; 1,2,4-Triazole-3-carboxamide, 1-(β-D-ribofuranosyl)-; Ribavirin Impurity; Ribavirin Related Compound; 1-(β-D-Ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide; 1-(β-D-Ribofuranosyl)-1,2,4-triazole-3-carboxamide (enantiomer)
EINECS	Contact for details

Quality Control

Our 1-[(2S,3S,4S,5S)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-1,2,4-Triazole-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, related substances, and residual solvents are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.