Description

4,5-Difluoro-2-Hydroxy-Benzoic Acid is a fluorinated benzoic acid derivative that serves as a versatile and high-value synthetic intermediate. Its molecular structure, featuring both hydroxyl and carboxylic acid functional groups on a difluorinated aromatic ring, makes it a critical building block for creating complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and advanced material synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic semiconductors and liquid crystal compounds used in display technologies.
• Complex Ligand & Chelator Preparation: Employed in coordination chemistry to create specialized ligands for catalysis or metal ion sequestration.
• Advanced Polymer Modification: Incorporated into polymer backbones to impart specific characteristics like chemical resistance, thermal stability, or unique optical properties.
• Academic & Contract Research: Essential reagent for organic synthesis research in universities and contract research organizations (CROs) exploring new fluorination methodologies and heterocyclic chemistry.

Basic Information

Product Name	4,5-Difluoro-2-Hydroxy-Benzoic Acid
CAS No.	205533-31-9
Molecular Formula	C7H4F2O3
Molecular Weight	174.10 g/mol
Synonyms	2-Hydroxy-4,5-difluorobenzoic Acid; 4,5-Difluorosalicylic Acid; 4,5-Difluoro-2-hydroxybenzenecarboxylic Acid; Benzoic acid, 2-hydroxy-4,5-difluoro-; 205533-31-9; 4,5-DFHBA; 4,5-Difluorosalycylic Acid
EINECS	Contact for details

Quality Control

Our 4,5-Difluoro-2-Hydroxy-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.