Description

(S)-tert-Butyl 2-(Hydroxymethyl)-2,5-Dihydro-1H-Pyrrole-1-Carboxylate CAS NO 205444-34-4 is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing stereochemically defined pyrrolidine-based scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Asymmetric Synthesis: Serves as a versatile precursor for constructing complex, enantiomerically pure molecules in medicinal chemistry and process development.
• Agrochemical Research: Used in the development of chiral active ingredients for crop protection products.
• Ligand and Catalyst Development: Acts as a starting material for the preparation of chiral ligands and organocatalysts used in stereoselective transformations.
• Academic & Contract Research: Employed in research laboratories for method development and the exploration of new synthetic pathways.
• Fine Chemical Production: Utilized in the custom synthesis of high-value, specialty chemicals for various industrial applications.

Basic Information

Product Name	(S)-tert-Butyl 2-(Hydroxymethyl)-2,5-Dihydro-1H-Pyrrole-1-Carboxylate
CAS No.	205444-34-4
Molecular Formula	C10H17NO3
Molecular Weight	199.25 g/mol
Synonyms	1-Boc-2-(hydroxymethyl)-2,5-dihydro-1H-pyrrole; (S)-1-Boc-2-(hydroxymethyl)-2,5-dihydro-1H-pyrrole; (S)-1-(tert-Butoxycarbonyl)-2-(hydroxymethyl)-2,5-dihydro-1H-pyrrole; (S)-2-(Hydroxymethyl)-1-N-Boc-2,5-dihydropyrrole; (S)-N-Boc-2-(hydroxymethyl)-2,5-dihydro-1H-pyrrole; tert-Butyl (S)-2-(hydroxymethyl)-2,5-dihydro-1H-pyrrole-1-carboxylate; (S)-1-Boc-2,5-dihydro-1H-pyrrole-2-methanol
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 2-(Hydroxymethyl)-2,5-Dihydro-1H-Pyrrole-1-Carboxylate is manufactured under strict quality control protocols to ensure high chemical purity and enantiomeric excess suitable for research and development applications. All batches are supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral purity. We adhere to cGMP principles where applicable to support pharmaceutical development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.