Description

Benzeneacetic Acid, α-(1-Hydroxycyclopentyl)-, 2-(Dimethylamino)Ethyl Ester, (S)- is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters for its role as a key building block in the development of enantiomerically pure active pharmaceutical ingredients (APIs), where stereochemical control is critical for efficacy and safety. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and production of enantiomerically pure drug candidates.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex target molecules, particularly in central nervous system (CNS) and other specialty therapeutics.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to introduce stereogenic centers.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale manufacturing for new chemical entities (NCEs).
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.

Basic Information

Product Name	Benzeneacetic Acid, α-(1-Hydroxycyclopentyl)-, 2-(Dimethylamino)Ethyl Ester, (S)-
CAS No.	204990-63-6
Molecular Formula	C17H25NO3
Molecular Weight	291.39 g/mol
Synonyms	(S)-2-(Dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate; (S)-α-(1-Hydroxycyclopentyl)benzeneacetic Acid 2-(Dimethylamino)ethyl Ester; (S)-Tropicamide Related Compound; (S)-N,N-Dimethyl-2-[(1S)-1-hydroxycyclopentylacetyl]oxy]ethanamine; (S)-Enantiomer of Cyclopentolate Precursor; (S)-2-Phenyl-2-(1-hydroxycyclopentyl)acetic Acid 2-(Dimethylamino)ethyl Ester
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, α-(1-Hydroxycyclopentyl)-, 2-(Dimethylamino)Ethyl Ester, (S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Enantiomeric Excess)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.