Description

L-Cysteine (15N) is a stable isotope-labeled derivative of the essential amino acid L-Cysteine, where the nitrogen atoms are enriched with the 15N isotope. This product is critical for advanced research applications requiring precise metabolic tracing and quantification, particularly in proteomics, metabolomics, and pharmacokinetic studies. It is an indispensable tool for scientists and manufacturers in the pharmaceutical, biotechnology, and academic research sectors who require high-fidelity isotopic labels for mass spectrometry and NMR analysis.

Application

• As an internal standard for the accurate quantification of L-Cysteine and related metabolites in biological samples via Mass Spectrometry (MS).
• For metabolic pathway tracing and flux analysis in cell culture and in vivo studies to understand sulfur and nitrogen metabolism.
• In the synthesis of isotopically labeled peptides, proteins, and other biomolecules for structural elucidation using Nuclear Magnetic Resonance (NMR) spectroscopy.
• As a key component in clinical research and diagnostic assay development for conditions related to oxidative stress and amino acid imbalances.
• For use in pharmaceutical research, including drug metabolism and pharmacokinetics (DMPK) studies of cysteine-containing compounds.

Basic Information

Product Name	L-Cysteine (15N)
CAS No.	204523-09-1
Molecular Formula	C3H7NO2S * (15N)
Molecular Weight	Contact for details
Synonyms	(2R)-2-Amino-3-sulfanylpropanoic-15N acid; L-Cysteine-15N; Cysteine-15N; (R)-2-Amino-3-mercaptopropionic-15N acid; 3-Mercapto-L-alanine-15N; 15N Labeled L-Cysteine; L-Cysteine (Nitrogen-15); Isotope-labeled Cysteine
EINECS	Contact for details

Quality Control

Every batch of our L-Cysteine (15N) is produced and analyzed under strict quality management protocols to ensure exceptional isotopic and chemical purity, which is paramount for research integrity. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (atom % 15N), chemical purity by HPLC, chiral purity, and specific tests for related substances. Our quality systems are designed to meet the rigorous demands of analytical and synthetic laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider under an inert atmosphere. Keep container tightly sealed when not in use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (atom % 15N)	≥ 98%
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]D20: +8.0° to +10.0° (c=1 in 1N HCl)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.