Description

Tebanicline (Hydrochloride) CAS NO 203564-54-9 is a high-purity, small molecule pharmaceutical reference standard and active pharmaceutical ingredient (API) intermediate. This compound is of significant interest in neuroscience research and pharmaceutical development due to its pharmacological profile. It is primarily utilized by research institutions, pharmaceutical R&D departments, and contract manufacturing organizations (CMOs) engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in API manufacturing.
• Neuroscience Research: Serves as a key biochemical tool for studying receptor interactions and signal transduction pathways in preclinical models.
• Active Pharmaceutical Ingredient (API) Intermediate: Employed in the multi-step synthesis of advanced drug candidates targeting the central nervous system.
• Process Development & Optimization: Used by process chemists to scale up and optimize synthetic routes for commercial production.
• Contract Research & Manufacturing (CRMO): Supplied to organizations providing custom synthesis and development services.
• Analytical Testing & Impurity Profiling: Acts as a primary standard for HPLC, LC-MS, and NMR analysis to identify and quantify related substances.

Basic Information

Product Name	Tebanicline (Hydrochloride)
CAS No.	203564-54-9
Molecular Formula	C11H14Cl2N2 • HCl
Molecular Weight	277.61 g/mol (free base: 241.15 g/mol)
Synonyms	Tebanicline HCl; (E)-N-Methyl-4-[3-(5,6-dichloro-3-pyridinyl)acryloyl]piperidine hydrochloride; ABT-594 Hydrochloride; EpiBatidine Analog; 5,6-Dichloro-3-pyridineacryloylpiperidine Hydrochloride; (E)-N-Methyl-4-[3-(5,6-dichloro-3-pyridinyl)-2-propenoyl]piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our Tebanicline (Hydrochloride) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, residual solvent analysis (GC), and identification by IR and NMR, to ensure it meets stringent specifications for research and development use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (HPLC)	97.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.