Description

Adenosine-1’-13C is a stable isotope-labeled analog of adenosine, a fundamental nucleoside in biochemistry. This product is essential for advanced research and development, providing a critical tool for metabolic pathway tracing and quantitative analysis using techniques like mass spectrometry and NMR. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for drug metabolism studies, biomarker discovery, and the development of labeled internal standards.

Application

• Metabolic Flux Analysis (MFA): Used as a 13C-labeled tracer to study and quantify intracellular metabolic pathways in cell cultures and microorganisms.
• Drug Metabolism and Pharmacokinetics (DMPK): Serves as an internal standard in LC-MS/MS for the accurate quantification of adenosine and its metabolites in biological matrices.
• Biomarker Research: Enables precise tracking of purine metabolism alterations associated with various disease states, including cardiovascular and inflammatory conditions.
• Enzymology Studies: Employed in kinetic and mechanistic studies of enzymes that utilize adenosine, such as kinases, deaminases, and nucleoside transporters.
• Diagnostic Assay Development: Integral for creating calibration standards and controls in clinical diagnostic kits measuring adenosine-related biomarkers.
• NMR Spectroscopy: Provides a non-radioactive, stable isotopic label for structural and dynamic studies of biomolecules and their interactions.

Basic Information

Item	Detail
Product Name	Adenosine-1’-13C
CAS No.	201996-55-6
Molecular Formula	C10H12N5O4 (with 13C at the 1' position)
Molecular Weight	Contact for details
Synonyms	1'-13C-Adenosine; Adenosine (1'-13C); 9-β-D-Ribofuranosyladenine-1'-13C; 6-Amino-9-β-D-ribofuranosyl-9H-purine-1'-13C; 13C Labeled Adenosine; Stable Isotope Labeled Adenosine; Adenosine-13C1; [1'-13C]Adenosine
EINECS	Contact for details

Quality Control

Every batch of Adenosine-1’-13C is produced and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, isotopic enrichment, and specific tests is provided with each shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.