Description

D-[1,2-13C2]Xylose is a stable isotope-labeled analog of the pentose sugar D-xylose, specifically enriched with carbon-13 at the 1 and 2 positions. This high-purity labeled compound is essential for advanced metabolic research and analytical method development, providing a critical tracer for precise quantification. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic manufacturers engaged in carbohydrate metabolism studies, isotopic dilution mass spectrometry, and NMR spectroscopy.

Application

• Isotopic Tracer in Metabolic Pathway Analysis: Used to trace and quantify the flux of xylose through biochemical pathways in microbial, plant, and mammalian systems.
• Internal Standard for Quantitative Mass Spectrometry (MS): Serves as a critical internal standard in LC-MS and GC-MS methods for the accurate measurement of endogenous D-xylose levels in complex biological matrices.
• NMR Spectroscopy Studies: Enables detailed structural and dynamic studies of carbohydrate metabolism and enzyme mechanisms due to the distinct 13C NMR signals.
• Pharmaceutical Research & Drug Development: Supports research into drugs targeting carbohydrate-processing enzymes and metabolic disorders.
• Diagnostic Assay Development: Employed in the calibration and validation of clinical diagnostic tests, such as those for intestinal permeability and malabsorption.
• Nutritional Science Research: Used to investigate the digestion, absorption, and fermentation of dietary fibers and prebiotics.

Basic Information

Product Name	D-[1,2-13C2]Xylose
CAS No.	201741-00-6
Molecular Formula	C3¹³C2H10O5
Molecular Weight	152.10 g/mol
Synonyms	(1,2-13C2)-D-Xylose; D-Xylose-1,2-13C2; [1,2-13C2]Xylose; 13C Labeled D-xylose; D-Xylopyranose-1,2-13C2; Isotopically Labeled Xylose; Xylose-1,2-13C2; Stable Isotope-Labeled Pentose
EINECS	Contact for details

Quality Control

Every batch of D-[1,2-13C2]Xylose is manufactured and analyzed under strict quality management protocols to ensure exceptional isotopic and chemical purity. Our products undergo rigorous quality testing, including isotopic enrichment analysis by NMR and MS, chemical purity assessment by HPLC, and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results for isotopic purity, chemical purity, and residual solvents are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Isotopic Enrichment (13C)	≥ 99 atom % 13C at positions 1 & 2
Chemical Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	+18.5° to +19.5° (c=10 in H2O)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.