Description

L-Cysteine (3-13C) is a stable isotope-labeled derivative of the essential amino acid L-Cysteine, specifically labeled with carbon-13 at the 3-position. This high-purity labeled compound is critical for advanced research and development, enabling precise metabolic pathway tracing and quantitative analysis in complex biological systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for applications requiring high isotopic enrichment and chemical purity.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to study sulfur amino acid metabolism, glutathione synthesis, and energy pathways in cell cultures and animal models.
• Pharmaceutical Research & Development: Serves as an internal standard for the accurate quantification of L-Cysteine and related metabolites in bioanalytical methods using LC-MS and GC-MS.
• Nutraceutical & Clinical Research: Enables studies on the bioavailability, pharmacokinetics, and biochemical roles of cysteine in dietary supplements and therapeutic formulations.
• Biochemical Synthesis: Acts as a labeled building block for the synthesis of more complex isotopically labeled peptides, proteins, and other biomolecules.
• Diagnostic Agent Development: Employed in the research and production of labeled compounds for use in advanced medical diagnostics and imaging.

Basic Information

Product Name	L-Cysteine (3-13C)
CAS No.	201612-57-9
Molecular Formula	C313CH7NO2S
Molecular Weight	122.16 g/mol (for 12C form, Contact for exact labeled MW)
Synonyms	(2R)-2-Amino-3-((13C)carboxy)sulfanylpropanoic Acid; L-Cysteine-3-13C; L-Cysteine (3-13C); (13C)Cysteine; Cysteine-13C; 3-13C-L-Cysteine; (R)-2-Amino-3-((13C)mercapto)propanoic Acid; Labeled L-Cysteine
EINECS	Contact for details

Quality Control

Our L-Cysteine (3-13C) is manufactured under strict quality control protocols to ensure exceptional isotopic and chemical purity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (Atom % 13C), chemical purity (by HPLC), chiral purity, and residual solvent content. We adhere to cGMP principles for research-grade materials, ensuring consistency, traceability, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its sensitivity to oxidation and moisture. For long-term storage, desiccate and keep frozen at -20°C or below.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (Atom % 13C)	≥ 99% (or as specified)
Assay (HPLC)	≥ 98.0%
Chiral Purity ([α]D)	≥ 99.0% L-Isomer
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.