Description

D-[Ul-13C6]Fructose is a uniformly carbon-13 labeled isotopologue of the natural sugar D-fructose, where all six carbon atoms are the stable isotope 13C. This high-purity labeled compound is essential for advanced metabolic research, enabling precise tracking and quantification of fructose pathways in biological systems using techniques like NMR spectroscopy and mass spectrometry. It is a critical reagent for pharmaceutical development, nutritional studies, and biochemical research requiring high isotopic enrichment and chemical purity.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to map and quantify central carbon metabolism in cells, tissues, or whole organisms.
• Drug Metabolism & Pharmacokinetics (DMPK): Serves as an internal standard for the accurate LC-MS/MS quantification of fructose and its metabolites in biological fluids.
• Nutritional & Biomedical Research: Investigates fructose absorption, utilization, and its role in metabolic disorders such as diabetes and non-alcoholic fatty liver disease (NAFLD).
• NMR Spectroscopy: Provides superior signal sensitivity for structural and dynamic studies of carbohydrate-protein interactions and enzymatic mechanisms.
• Stable Isotope Labeling: Used in the synthesis of more complex 13C-labeled compounds for use as probes or standards.
• Quality Control & Method Development: Acts as a certified reference material (CRM) for calibrating analytical instruments and validating assay methods in regulatory environments.

Basic Information

Product Name	D-[Ul-13C6]Fructose
CAS No.	201595-65-5
Molecular Formula	13C6H12O6
Molecular Weight	186.10 g/mol (for 13C6)
Synonyms	D-Fructose-13C6; (3S,4R,5R)-1,3,4,5,6-Pentahydroxyhexan-2-one-13C6; Fructose (U-13C6); Uniformly Labeled 13C6 Fructose; [U-13C]-D-Fructose; 13C6-Fructose; D-(-)-Fructose-13C6
EINECS	Contact for details

Quality Control

Our D-[Ul-13C6]Fructose is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >99 atom % 13C), chemical purity (by HPLC), and specific analytical data. We support compliance with relevant standards for research chemicals and can provide materials suitable for use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Specific Optical Rotation	-91° to -95° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.