Description

Decahydro-3Soquinolinecarboxamidemonobenzoate,Nelfinavirmesylate is the mesylate salt form of nelfinavir, a potent and selective inhibitor of the HIV-1 protease enzyme. This compound is a critical active pharmaceutical ingredient (API) essential for the formulation of antiretroviral medications. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of therapies for the treatment of Human Immunodeficiency Virus (HIV) infection.

Application

• Active Pharmaceutical Ingredient (API): Primary use in the formulation of antiretroviral drugs for HIV/AIDS treatment.
• Pharmaceutical Research & Development: Serves as a key reference standard and intermediate in the development of new protease inhibitor therapies.
• Generic Drug Manufacturing: Essential for the production of generic versions of nelfinavir-based medications.
• Clinical Trial Material: Used in the preparation of investigational drugs for clinical studies.
• Biochemical Research: Utilized in virology and enzymology studies to understand HIV protease mechanism and inhibition.

Basic Information

Item	Details
Product Name	Decahydro-3Soquinolinecarboxamidemonobenzoate,Nelfinavirmesylate
CAS No.	201402-98-4
Molecular Formula	C32H45N3O4S · CH4O3S
Molecular Weight	663.88 g/mol
Synonyms	Nelfinavir Mesylate; AG1343 Mesylate; Viracept (Brand Name Mesylate Salt); (3S,4aS,8aS)-N-(1,1-Dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-(4aS,8aS)-3-isoquinolinecarboxamide monomethanesulfonate; HIV Protease Inhibitor AG1343 Mesylate; NSC 716051
EINECS	Contact for details

Quality Control

Our Nelfinavir Mesylate is manufactured under strict quality systems. Each batch is tested to ensure it meets stringent specifications for identity, purity, and potency, aligning with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and microbiological attributes is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5%; Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Microbiological Enumeration	Total aerobic microbial count ≤ 1000 cfu/g; Total combined yeasts/molds ≤ 100 cfu/g
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.