Description

Tenofovir Prodrug CAS NO 201341-01-7 is a key pharmaceutical intermediate, specifically a prodrug form of the potent antiviral agent Tenofovir. This compound is critical for enhancing the bioavailability and therapeutic efficacy of Tenofovir-based medications. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of advanced antiviral therapies.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Primary intermediate in the manufacturing of Tenofovir Disoproxil Fumarate (TDF) and Tenofovir Alafenamide (TAF).
• Antiviral Drug Development: Core building block for research and production of nucleoside reverse transcriptase inhibitor (NRTI) class medications.
• Hepatitis B Treatment: Used in the synthesis of APIs for chronic Hepatitis B virus (HBV) therapeutics.
• HIV/AIDS Treatment: Essential in the supply chain for combination antiretroviral therapies (cART) targeting HIV-1.
• Pharmaceutical Research: Serves as a reference standard and starting material for novel prodrug design and metabolic studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and commercial production.

Basic Information

Product Name	Tenofovir Prodrug
CAS No.	201341-01-7
Molecular Formula	C19H30N5O10P
Molecular Weight	519.44 g/mol
Synonyms	Tenofovir Disoproxil; (R)-9-(2-Phosphonomethoxypropyl)adenine Bis(isopropoxycarbonyloxymethyl) Ester; Bis(POC) PMPA; GS 4331; Viread Intermediate; TDF Intermediate; PMPA Bis(POC) Ester; Gilead 4331
EINECS	Contact for details

Quality Control

Our Tenofovir Prodrug is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) are available for every batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with ICH guidelines, and we can support documentation for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.