Description

Thymine-13C1 is a stable isotope-labeled analog of the nucleobase thymine, where one carbon atom is replaced with the carbon-13 isotope. This product is essential for advanced analytical and research applications requiring precise molecular tracking and quantification. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, metabolomics, and stable isotope tracer studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analysis for accurate measurement of endogenous thymine and related metabolites.
• Metabolic Pathway Tracing: Employed in in vitro and in vivo studies to elucidate nucleotide metabolism, DNA synthesis, and cell proliferation pathways.
• Pharmaceutical Research & Development: Critical for drug metabolism and pharmacokinetics (DMPK) studies of nucleoside analog drugs.
• Diagnostic Assay Development: Serves as a key component in the development of clinical diagnostic kits for metabolic disorders and oncology.
• Biochemical Research: Used in enzymatic studies and as a building block for synthesizing isotopically labeled nucleosides and nucleotides.

Basic Information

Product Name	Thymine-13C1
CAS No.	200417-68-1
Molecular Formula	C413CH6N2O2
Molecular Weight	127.10 g/mol
Synonyms	5-Methyl-2,4(1H,3H)-pyrimidinedione-13C1; 5-Methyluracil-13C1; 2,4-Dihydroxy-5-methylpyrimidine-13C1; Thymine-5-13C; [5-13C]-Thymine; Isotopically labeled thymine; 13C Labeled thymine; 13C1-Thymine
EINECS	Contact for details

Quality Control

Our Thymine-13C1 is manufactured under strict quality control protocols to ensure high isotopic and chemical purity, essential for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >99 atom % 13C), chemical purity (by HPLC), and identity confirmation. We adhere to relevant industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥99 atom % 13C
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.