Description

Toloxatone CAS NO 29218-27-7 is a selective and reversible inhibitor of monoamine oxidase A (MAO-A), belonging to the chemical class of oxazolidinones. This compound is of significant interest for its role in the research and development of central nervous system (CNS) active pharmaceuticals. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in the synthesis of advanced intermediates or active pharmaceutical ingredients (APIs) for neurological applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of antidepressant and neuropsychiatric drug candidates.
• Biochemical Research: Used as a reference standard or tool compound in studies investigating monoamine oxidase enzyme kinetics and inhibition mechanisms.
• Preclinical Development: Serves as a critical material in the formulation and efficacy testing of novel MAO-A inhibitor prototypes.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex molecules with targeted neurological activity.
• Reference Standard: Supplied with certified purity for use in analytical method development, validation, and quality control laboratories.

Basic Information

Product Name	Toloxatone
CAS No.	29218-27-7
Molecular Formula	C12H15NO3
Molecular Weight	221.25 g/mol
Synonyms	5-(Hydroxymethyl)-3-(3-methylphenyl)-2-oxazolidinone; 3-m-Tolyl-5-hydroxymethyl-2-oxazolidinone; Humoryl; Perenum; MD 69276; Toloxaton; Toloxatona; Toloxatonum
EINECS	249-499-3

Quality Control

Our Toloxatone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting results for key parameters including assay, related substances, and residual solvents. We support compliance with global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to atmospheric moisture and light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.