Description

3-Hydroxy-1-Methylquinuclidinium Bromide α-Cyclopentylmandelate is a high-purity, specialized pharmaceutical intermediate and active ingredient. This compound matters for its critical role in the synthesis of advanced therapeutic agents, particularly in the cholinergic and anticholinergic drug classes. It is primarily needed by research institutions and pharmaceutical manufacturers developing treatments for neurological and ophthalmic conditions, where precise chemical structure and purity are paramount for efficacy and safety.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of anticholinergic and antimuscarinic drugs.
• Active Pharmaceutical Ingredient (API): Used in the formulation of ophthalmic solutions for conditions like mydriasis and cycloplegia.
• Neurological Research: Serves as a reference standard and tool compound in studies targeting muscarinic acetylcholine receptors.
• Preclinical Development: Utilized in the development and scale-up of novel therapeutic candidates for gastrointestinal and urinary tract spasms.
• Chemical Synthesis: Employed in organic synthesis for introducing the quinuclidine moiety into complex molecules.
• Quality Control: Acts as an analytical standard for HPLC and spectroscopic methods in pharmaceutical quality assurance labs.

Basic Information

Product Name	3-Hydroxy-1-Methylquinuclidinium Bromide α-Cyclopentylmandelate
CAS No.	29125-57-3
Molecular Formula	C20H30BrNO4
Molecular Weight	428.36 g/mol
Synonyms	Cyclopentolate Hydrobromide; Cyclopentolate HBr; 1-Hydroxy-α-cyclopentylbenzeneacetic acid 2-(dimethylamino)ethyl ester hydrobromide; 3-Hydroxy-1-methylquinuclidinium bromide α-cyclopentylmandelate; α-Cyclopentyl-α-hydroxybenzeneacetic acid 2-(dimethylamino)ethyl ester hydrobromide; Cyclogyl (as active ingredient); AK-Pentolate; Pentolair
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-1-Methylquinuclidinium Bromide α-Cyclopentylmandelate is manufactured under strict quality systems. It undergoes rigorous analytical testing to ensure compliance with pharmaceutical-grade standards, including identity, purity, and impurity profile verification. Certificates of Analysis (COA) detailing results from HPLC, NMR, and other pharmacopeial methods are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity to prevent degradation and maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.