Description

β-Pilocarpine Hydrochloride is a high-purity cholinergic agonist salt, essential for precise pharmacological research and development. This compound is valued for its consistent quality and stability, making it a critical raw material for advanced pharmaceutical formulations. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on ophthalmic solutions, neurological studies, and the development of parasympathomimetic agents.

Application

• Ophthalmic Pharmaceutical Manufacturing: As a key active pharmaceutical ingredient (API) in formulations for the treatment of glaucoma and other intraocular pressure disorders.
• Neurological Research: Used as a selective muscarinic receptor agonist in preclinical studies to investigate cholinergic pathways and related disorders.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Pilot-Scale Synthesis: Employed in the development and scale-up of novel drug delivery systems, including sustained-release formulations.
• Biochemical Assays: Utilized in in vitro studies to stimulate salivary, sweat, or gastric secretion for physiological research.

Basic Information

Product Name	β-Pilocarpine Hydrochloride
CAS No.	28958-85-2
Molecular Formula	C11H17ClN2O2
Molecular Weight	244.72 g/mol
Synonyms	Pilocarpine Hydrochloride (beta form); (3S,4R)-3-Ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one hydrochloride; Pilocarpine HCl; Isopilocarpine Hydrochloride; 5-[(4-Ethyl-5-oxotetrahydrofuran-2-yl)methyl]-1-methylimidazole hydrochloride
EINECS	Contact for details

Quality Control

Our β-Pilocarpine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications suitable for pharmaceutical research. Certificates of Analysis (COA) documenting compliance with relevant standards are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5%
Specific Rotation	+84° to +90° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.