Description

(R)-3-Hydroxy-1-Methyl-Piperidine CAS NO 28808-26-6 is a chiral piperidine derivative, a crucial building block in modern asymmetric synthesis. Its value lies in its stereochemically defined hydroxyl group, which enables the precise construction of complex molecules with high enantiomeric purity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of various therapeutic agents, including central nervous system (CNS) drugs and receptor modulators.
• Asymmetric Catalyst Ligand Precursor: Used to develop and synthesize novel chiral ligands for transition metal catalysis.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure pesticides and herbicides.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating compound libraries in medicinal chemistry.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high stereochemical fidelity.

Basic Information

Product Name	(R)-3-Hydroxy-1-Methyl-Piperidine
CAS No.	28808-26-6
Molecular Formula	C6H13NO
Molecular Weight	115.17 g/mol
Synonyms	(R)-1-Methyl-3-hydroxypiperidine; (R)-1-Methylpiperidin-3-ol; (3R)-1-Methyl-3-piperidinol; (R)-3-Hydroxy-1-methylpiperidine; (R)-N-Methyl-3-piperidinol; (R)-1-Methyl-3-piperidinol; (R)-3-Piperidinol, 1-methyl-; 28808-26-6
EINECS	Contact for details

Quality Control

Our (R)-3-Hydroxy-1-Methyl-Piperidine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.