Description

5-Iodoisobenzofuran-1,3-Dione is a halogenated phthalimide derivative, a versatile and high-value organic intermediate. Its core value lies in its unique reactivity, where the iodine atom serves as an excellent leaving group for cross-coupling reactions, enabling the synthesis of complex heterocyclic and pharmaceutical scaffolds. This compound is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex heterocyclic cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science: Serves as a precursor for functional organic materials, including organic semiconductors and liquid crystals.
• Cross-Coupling Reactions: The iodine moiety facilitates Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized iodinated dyes and colorants.

Basic Information

Product Name	5-Iodoisobenzofuran-1,3-Dione
CAS No.	28418-89-5
Molecular Formula	C8H3INO3
Molecular Weight	273.02 g/mol
Synonyms	5-Iodophthalimide; 5-Iodo-1H-isoindole-1,3(2H)-dione; 5-Iodoisoindoline-1,3-dione; 1,3-Dioxo-5-iodoisoindoline; 5-Iodo-1,3-dihydro-2H-isoindole-1,3-dione; 5-Iodophthalic acid imide
EINECS	Contact for details

Quality Control

Our 5-Iodoisobenzofuran-1,3-Dione is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.