Description

4-Bromo-2,5-Difluorobenzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. This compound is valued for its unique halogenated and fluorinated structure, which enables precise molecular modifications in complex chemical architectures. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogen and fluorine substitution for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluoro and bromo groups contribute to target specificity and efficacy.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic electronic materials, contributing to the development of high-performance display and lighting technologies.
• Polymer Chemistry: Employed as a monomer or modifier to introduce fluorine and bromine functionalities into specialty polymers, enhancing properties like chemical resistance and thermal stability.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine atom, facilitating carbon-carbon bond formation.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel fluorinated compound libraries.

Basic Information

Product Name	4-Bromo-2,5-Difluorobenzoic Acid
CAS No.	28314-82-1
Molecular Formula	C7H3BrF2O2
Molecular Weight	236.99 g/mol
Synonyms	2,5-Difluoro-4-bromobenzoic Acid; Benzoic acid, 4-bromo-2,5-difluoro-; 4-Bromo-2,5-difluorobenzoic acid; 4-Bromo-2,5-difluoro-benzoic acid; 28314-82-1; 2,5-Difluoro-4-bromo-benzoic acid; 4-Br-2,5-F2-C6H2-CO2H
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,5-Difluorobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.