Description

2,4,6-Trifluorobenzoic Acid is a versatile fluorinated aromatic building block essential for advanced organic synthesis. Its value lies in the unique electronic and steric properties imparted by the symmetrical trifluoro substitution pattern, which is critical for modulating the reactivity and physical characteristics of target molecules. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving their dielectric anisotropy and thermal stability.
• Polymer Modification: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance and unique surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a precursor for other fluorinated benzoic acid derivatives.
• Coordination Chemistry & Ligand Design: Useful for synthesizing fluorinated ligands for metal-organic frameworks (MOFs) and catalysts.

Basic Information

Product Name	2,4,6-Trifluorobenzoic Acid
CAS No.	28314-80-9
Molecular Formula	C7H3F3O2
Molecular Weight	176.09 g/mol
Synonyms	Benzoic acid, 2,4,6-trifluoro-; 2,4,6-Trifluorobenzenecarboxylic acid; 2,4,6-Trifluorophenylcarboxylic acid; 2,4,6-Trifluorobenzene-1-carboxylic acid; 2,4,6-Trifluoro-benzoic acid; TFB Acid; 2,4,6-TFBA
EINECS	Contact for details

Quality Control

Our 2,4,6-Trifluorobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) documenting purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product quality. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	152 - 156 °C
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.