Description

(1S,2S)-(+)-2-Amino-1-Phenyl-1,3-Propanediol is a high-purity chiral amino diol building block of significant importance in asymmetric synthesis. Its defined stereochemistry makes it a valuable intermediate for constructing complex pharmaceutical molecules and fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of antibiotics, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• Agrochemical Synthesis: Serves as a building block for creating chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial Research: A valuable standard and starting material in methodological development for organic and medicinal chemistry.
• Resolution Agent: Can be utilized in the chiral resolution of racemic mixtures due to its own defined stereocenters.

Basic Information

Product Name	(1S,2S)-(+)-2-Amino-1-Phenyl-1,3-Propanediol
CAS No.	28143-91-1
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(+)-(1S,2S)-2-Amino-1-phenyl-1,3-propanediol; (1S,2S)-2-Amino-1-phenylpropane-1,3-diol; D-erythro-2-Amino-1-phenyl-1,3-propanediol; (1S,2S)-APD; (S,S)-APD; Phenylamino propanediol; 1-Phenyl-2-amino-1,3-propanediol (S,S-isomer); Lincosamine derivative
EINECS	Contact for details

Quality Control

Our (1S,2S)-(+)-2-Amino-1-Phenyl-1,3-Propanediol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity (HPLC), chemical assay, and identification, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.